It is a way of fertilization based on the sperm’s and oocyte’s physiology, hence the name Physiological ICSI (PICSI).
Its difference with ICSI is in the use of special plates and culture mediums where small quantities of processed sperm sample of the husband are placed.
In this material the binding of immature sperm forms is impossible because they do not have the suitable receptors. On the contrary, spermatozoa with distinctly limited chromosome aberrations and significant improvement of their nucleus’ maturation are bound and selected for fertilization.
In each technique (IMSI or PICSI), used either separately or in combination, we select mature and morphologically normal spermatozoa.
Especially for the PICSI method, which is used extensively in the IVF Athens Center, there is distinct improvement of the embryo quality, increased chance of implantation, increase on the rate of clinical pregnancies and decrease of the clinical miscarriages.